Article
Antimicrobial peptides signal need for sleep from peripheral wounds to the nervous system
2020-07-03
Abstract excerpt
Wounding triggers a protective innate immune response that includes the production of antimicrobial peptides and increased sleep. Little is known, however, about how peripheral wounds signal need for sleep to the nervous system. We found that during C. elegans larval molting, a tolloid/BMP-1-like protein promotes sleep through an epidermal innate immune pathway and the expression of more than a dozen antimicrobia...
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Identifiers and source
- Literature Corpus work
- 0dda05fe-2d68-5437-908a-c02eedb8d769
- DOI
- 10.1101/2020.07.02.183806