Article

Gut-innervating nociceptor neurons protect against enteric infection by modulating the microbiota and Peyer’s patch microfold cells

2019-03-21

Abstract excerpt

<h4>SUMMARY</h4> Gut-innervating nociceptor sensory neurons respond to noxious/tissue-damaging stimuli by initiating protective responses and releasing mediators that regulate tissue inflammation, gastrointestinal secretion, and motility. The role of nociceptors in host defense against enteric pathogens is unclear. Here, we found that gut-extrinsic nociceptor neurons are critical in protecting the host against S...

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Literature Corpus work: 0e81f5ec-502c-57ec-94af-365e0305669a
DOI: 10.1101/580555

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