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Diminished nuclear-localized β-adrenergic signaling activates YAP to promote kidney fibrosis in diabetic nephropathy

2024-09-01

Abstract excerpt

<h4>Background: </h4> and purpose Diabetic nephropathy (DN) is a leading cause of chronic kidney diseases (CKD) characterized by mesangial matrix expansion that involves dysfunctional mesangial cells (MCs). However, the underlying mechanisms remain unclear. This study aims to delineate the spatiotemporal contribution of adrenergic signaling in diabetic kidney fibrosis to reveal potential therapeutic target. Experi...

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Literature Corpus work
0dac4a50-1bdc-5c0c-a322-99f66ae42571
DOI
10.22541/au.172518446.62912572/v1
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Diminished nuclear-localized β-adrenergic signaling activates YAP to promote kidney fibrosis in diabetic nephropathyDOI 10.22541/au.172518446.62912572/v1
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