Article

An anti-cancer cell therapy platform utilizing ex vivo physiologic dendritic cells expressing mRNA-encoded antigens and immune checkpoint blockers

2025-05-30

Abstract excerpt

<title>Abstract</title> Therapeutic vaccines have struggled to effectively combat cancer. The core challenge lies in generating a durable and diverse immune response capable of eradicating tumors. The limited clinical success of therapeutic vaccination attempts highlights the need for new strategies that combine robust T cell memory induction with immune checkpoint blockade (ICB) delivery at the antigen presen...

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Literature Corpus work: 0d736cb6-bf87-5449-b1f5-6dac0e8c1b09
DOI: 10.21203/rs.3.rs-6480245/v1

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