Article

Structural basis of canonical TIR-NLR activation in plant innate immunity

2026-02-06

Abstract excerpt

<h4>Summary</h4> In plants, intracellular NLRs (nucleotide-binding leucine-rich repeat receptors) detect pathogen effector proteins, form oligomeric resistosomes, and activate ETI (effector-triggered immunity). NLRs contain N-terminal signaling, central NB-ARC (nucleotide-binding) and C-terminal LRR (leucine-rich repeat) domains. NLRs with N-terminal TIR (Toll/interleukin-1 receptor) domains (TNLs) hydrolyze NAD...

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Literature Corpus work: 0d553e51-f55a-5ba3-9586-b262087cbeee
DOI: 10.64898/2026.02.03.703613

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