Article

Broader functions of TIR domains in Arabidopsis immunity

2022-12-23

Abstract excerpt

TIR domains are NAD-degrading enzymes that function during immune signaling in prokaryotes, plants, and animals. In plants, most TIR domains are incorporated into intracellular immune receptors. In Arabidopsis, TIR-derived small molecules bind and activate EDS1 heterodimers, which in turn activate RNLs, a class of cation channel-forming immune receptors. RNL activation drives cytoplasmic Ca 2+ influx, transcripti...

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Literature Corpus work: ce3f8ba3-fc46-529e-aed7-77a4e22eaff9
DOI: 10.1101/2022.12.23.521769

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