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Article

Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.

Nature - 1 Aug 2024

Ma Shoucai, An Chunpeng, Lawson Aaron W, Cao Yu, Sun Yue, Tan Eddie Yong Jun, Pan Jinheng, Jirschitzka Jan, Kümmel Florian, Mukhi Nitika, Han Zhifu, Feng Shan, Wu Bin, Schulze-Lefert Paul, Chai Jijie

Abstract excerpt

Nucleotide-binding leucine-rich repeat (NLR) proteins play a pivotal role in plant immunity by recognizing pathogen effectors1,2. Maintaining a balanced immune response is crucial, as excessive NLR expression can lead to unintended autoimmunity3,4. Unlike most NLRs, the plant NLR required for cell death 2 (NRC2) belongs to a small NLR group characterized by constitutively high expression without self-activation5....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38866053
DOI: 10.1038/s41586-024-07668-7
PMCID: PMC11338831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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