Article
The Arabidopsis TIRome informs the design of artificial TIR (Toll/interleukin-1 receptor) domain proteins
2025-03-17
Abstract excerpt
The TIR (Toll/interleukin-1 receptor) domain is an ancient protein module that functions in immune and cell death responses across the Tree of Life. TIR domains encoded by plants and prokaryotes function as enzymes to produce diverse small molecule immune signals. Plant genomes can encode hundreds of TIR-domain containing proteins – many of which confer important agricultural disease resistance as TIR-NLR (nucleot...
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Identifiers and source
- Literature Corpus work
- 93a2fada-cc6c-5d39-ba22-8545dc60bd2b
- DOI
- 10.1101/2025.03.15.643477
