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Integrative Multiomic and Deep Learning Profiling of KRAS Mutant and Wildtype Genomes in Pancreatic Tumorigenesis

2025-08-12

Abstract excerpt

<title>Abstract</title> <p>Pancreatic ductal adenocarcinoma exhibits high intertumoral heterogeneity, with KRAS mutations as the dominant oncogenic driver. However, a subset of these tumors retains a wild-type KRAS genotype yet progresses through alternative molecular mechanisms. Deciphering how these divergent tumors converge on shared malignant outcomes is crucial for precision oncology. We conducted an integra...

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Literature Corpus work
0d552dd5-8cf9-593c-b17f-35b274ff31d0
DOI
10.21203/rs.3.rs-7335783/v1
Open publication

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Integrative Multiomic and Deep Learning Profiling of KRAS Mutant and Wildtype Genomes in Pancreatic TumorigenesisDOI 10.21203/rs.3.rs-7335783/v1
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