Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pancreatic ductal adenocarcinomas from Mexican patients present a distinct genomic mutational pattern.

Molecular biology reports - 1 Jul 2020

Sanchez Paulina, Espinosa Magali, Maldonado Vilma, Barquera Rodrigo, Belem-Gabiño Nayeli, Torres Javier, Cravioto Adrian, Melendez-Zajgla Jorge

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers in humans, with less than 5% 5-year survival rate. PDAC is characterized by a small number of recurrent mutations, including KRAS, CDKN2A, TP53, and SMAD4 and a long "tail" of infrequent mutated genes. Most of the studies have been performed in US and European populations, so new studies are needed to describe the mutational landscape of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Gene Frequency

Share to Pancreatic Neoplasms

Share to Proto-Oncogene Proteins p21(ras)

Share to Smad4 Protein

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 32583281
DOI: 10.1007/s11033-020-05592-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pancreatic ductal adenocarcinomas from Mexican patients present a distinct genomic mutational pattern.PMID 32583281Read ↗

Molecular Pathology of Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Genetic landscape of pancreatic cancer: a narrative review.Semantic proximity Read ↗

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.Semantic proximity Read ↗

Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data.Semantic proximity Read ↗

Translational genomics in pancreatic ductal adenocarcinoma: A review with re-analysis of TCGA dataset.Semantic proximity Read ↗

Exome sequencing and digital PCR analyses reveal novel mutated genes related to the metastasis of pancreatic ductal adenocarcinoma.Semantic proximity Read ↗

Genomic Heterogeneity of Pancreatic Ductal Adenocarcinoma and Its Clinical ImpactSemantic proximity Read ↗

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.Semantic proximity Read ↗

Genomic Alterations and Their Clinical Implications in Pancreatic Ductal Adenocarcinoma in a Large-Scale Chinese Cohort.Semantic proximity Read ↗

Molecular Characterization of Pancreatic Ductal Adenocarcinoma Using a Next-Generation Sequencing Custom-Designed Multigene PanelSemantic proximity Read ↗

Molecular Profiling and Survival Outcomes in Pancreatic Ductal Adenocarcinoma: A Multicenter Real-World Study from Turkey.Semantic proximity Read ↗

Genetic Basis of Pancreas Cancer Development and Progression: Insights from Whole-Exome and Whole-Genome SequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.