Article

Structural determinants of calcium binding beyond the EF-hand binding site: a study of alpha parvalbumins

2020-09-20

Abstract excerpt

1 Parvalbumin (PV) is a calcium binding protein expressed in humans, fish and avian species. In these organisms, the calcium (Ca 2+ ) affinities of specific PV isoforms can vary by orders of magnitude. Despite the availability of high resolution structural data for many PV isoforms, the structural bases for how such proteins confer widely-varying divalent Ca 2+ affinities and selectivities against common ions li...

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Literature Corpus work: 0d22a9de-e2c8-5206-bc76-b6872348a2ca
DOI: 10.1101/2020.09.18.304063

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