Article
Molecular dynamics study of Ca(2+) binding loop variants of parvalbumin with modifications at the "gateway" position.
Protein engineering - 1 Feb 2001
Elkins K M, Gatzeva-Topalova P Z, Nelson D J
Abstract excerpt
The helix-loop-helix (i.e. EF-hand) Ca(2+) ion binding motif is characteristic of a large family of high-affinity Ca(2+) ion binding proteins, including the parvalbumins and calmodulins. In this paper we describe a set of molecular dynamics computations on the major parvalbumin from the silver ha...
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