Article

HEATR5B associates with dynein-dynactin and selectively promotes motility of AP1-bound endosomal membranes

2023-03-14

Abstract excerpt

<h4>ABSTRACT</h4> The dynein motor complex mediates polarised trafficking of a wide variety of organelles, intracellular vesicles and macromolecules. These functions are dependent on the dynactin complex, which helps recruit cargoes to dynein’s tail region and activates motor movement. How dynein and dynactin orchestrate trafficking of diverse cargoes is unclear. Here, we identify HEATR5B, an interactor of the AP...

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Literature Corpus work: 0d10ea5d-969a-54dd-ab00-cb14a25d4f6c
DOI: 10.1101/2023.03.14.532574

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