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Article

EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking.

The Journal of cell biology - 20 Jan 2003

Mills Ian G, Praefcke Gerrit J K, Vallis Yvonne, Peter Brian J, Olesen Lene E, Gallop Jennifer L, Butler P Jonathan G, Evans Philip R, McMahon Harvey T

Abstract excerpt

EpsinR is a clathrin-coated vesicle (CCV) enriched 70-kD protein that binds to phosphatidylinositol-4-phosphate, clathrin, and the gamma appendage domain of the adaptor protein complex 1 (AP1). In cells, its distribution overlaps with the perinuclear pool of clathrin and AP1 adaptors. Overexpression disrupts the CCV-dependent trafficking of cathepsin D from the trans-Golgi network to lysosomes and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12538641
DOI: 10.1083/jcb.200208023
PMCID: PMC2172650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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