Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel function of a dynein light chain in actin assembly during clathrin-mediated endocytosis.

The Journal of cell biology - 7 Aug 2017

Farrell Kristen B, McDonald Seth, Lamb Andrew K, Worcester Colette, Peersen Olve B, Di Pietro Santiago M

Abstract excerpt

Clathrin- and actin-mediated endocytosis is essential in eukaryotic cells. In this study, we demonstrate that Tda2 is a novel protein of the endocytic machinery necessary for normal internalization of native cargo in yeast. Tda2 has not been classified in any protein family. Unexpectedly, solving the crystal structure of Tda2 revealed it belongs to the dynein light chain family. However, Tda2 works independently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Actin-Related Protein 2-3 Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Actins

Share to Cytoskeletal Proteins

Share to Dyneins

Share to Electron Transport Chain Complex Proteins

Share to Endocytosis

Share to Microscopy, Video

Source

Open in PubMed Open full text

Identifiers

PMID: 28706108
DOI: 10.1083/jcb.201604123
PMCID: PMC5551697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel function of a dynein light chain in actin assembly during clathrin-mediated endocytosis.PMID 28706108Read ↗

Bicaudal D Family of Motor Adaptors: Linking Dynein Motility to Cargo Binding.Semantic proximity Read ↗

HEATR5B associates with dynein-dynactin and selectively promotes motility of AP1-bound endosomal membranesSemantic proximity Read ↗

AAGAB is an assembly chaperone regulating AP1 and AP2 clathrin adaptorsSemantic proximity Read ↗

In vivo andin vitro studies of adaptor-clathrin interaction.Semantic proximity Read ↗

Drebrin forms a cortical hub that connects actin, microtubules, and clathrin for endocytic transport of β2 integrinSemantic proximity Read ↗

Molecular mechanism and physiological functions of clathrin-mediated endocytosis.Semantic proximity Read ↗

Identification and dynamics of Arabidopsis adaptor protein-2 complex and its involvement in floral organ development.Semantic proximity Read ↗

A Novel Dynamin-Related Protein Has Been Recruited for Apicoplast Fission in Toxoplasma gondiiSemantic proximity Read ↗

Proximity labeling at non-centrosomal microtubule-organizing centers reveals VAB-10B and WDR-62 as distinct microtubule regulatorsSemantic proximity Read ↗

A novel function of Arp2p in mediating Prk1p-specific regulation of actin and endocytosis in yeast.Semantic proximity Read ↗

Direct comparison of clathrin-mediated endocytosis in budding and fission yeast reveals conserved and evolvable featuresSemantic proximity Read ↗

Yeast Aim21/Tda2 both regulates free actin by reducing barbed end assembly and forms a complex with Cap1/Cap2 to balance actin assembly between patches and cables.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.