Article
The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate chain-1.
Biochemical and biophysical research communications - 1 Mar 2001
Bielli A, Thörnqvist P O, Hendrick A G, Finn R, Fitzgerald K, McCaffrey M W
Abstract excerpt
Rab4 belongs to the Rab family of small GTPases involved in the regulation of intracellular transport, and has been localized to early endosomes. We have employed the yeast two-hybrid system to identify proteins that specifically interact with Rab4AQ67L, a GTPase-deficient mutant form of Rab4A. Screening a mouse embryo cDNA library identified a clone (M449) that interacted with Rab4A in a nucleotide-dependent...
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