Article

Neighboring codon adjacent nucleotides have a conserved influence on mRNA decay

2025-11-18

Abstract excerpt

<h4>Background</h4> Degeneracy in the genetic code has been shown to play a major role in yeast mRNA stability; differences in optimality (charged tRNA supply vs demand) among synonymous codons were revealed as a determinant of mRNA decay rates. However, whether and how much this mechanism determines mRNA decay rates in plants is unsettled. Furthermore, whether factors other than charged tRNA abundance influence...

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Literature Corpus work: 0cbdced4-29f0-56ee-995e-30085eebb9ec
DOI: 10.1101/2025.11.17.688958

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