Article

The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in <i>Drosophila</i> larvae

2022-11-08

Abstract excerpt

MLL -rearranged leukemias are among the leukemic subtypes with poorest survival, and treatment options have barely improved over the last decades. Furthermore, despite increasing molecular understanding of the mechanisms behind these hematopoietic malignancies, this knowledge has had poor translation into the clinic. Identification of novel treatment methods is hampered by the lack of relevant in vivo models that...

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Literature Corpus work: 0c9f5905-915a-5d92-b24c-e6d1e87aff33
DOI: 10.1101/2022.11.08.515565

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