Article

A sex-stratified genome-wide association study of tuberculosis using a multi-ethnic genotyping array

2018-08-31

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease with a known human genetic component. Males seem to be more affected than females and in most countries the TB notification rate is twice as high in males as in females. While socio-economic status, behaviour and sex hormones influence the male bias they do not fully account for it. Males have only one copy of the X chromosome, while dip...

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Literature Corpus work: 0c9e140c-e3dc-5fbd-a4e8-06145158cde1
DOI: 10.1101/405571

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