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The role of human host genetics in tuberculosis resistance.

Expert review of respiratory medicine - 1 Sept 2017

Kinnear Craig, Hoal Eileen G, Schurz Haiko, van Helden Paul D, Möller Marlo

Abstract excerpt

INTRODUCTION: Tuberculosis (TB) remains a public health problem: the latest estimate of new incident cases per year is a staggering 10.4 million. Despite this overwhelming number, the majority of the immunocompetent population can control infection with Mycobacterium tuberculosis. The human genome underlies the immune response and contributes to the outcome of TB infection. Areas covered: Investigations of TB...

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VDR gene
Genome-Wide Association Study
Genomics
Mycobacterium tuberculosis
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PMID: 28703045
DOI: 10.1080/17476348.2017.1354700

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