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Human global and population-specific genetic susceptibility to Mycobacterium tuberculosis infection and disease.

Current opinion in pulmonary medicine - 1 May 2020

Möller Marlo, Kinnear Craig J

Abstract excerpt

PURPOSE OF REVIEW: Multiple lines of evidence support a role of the host genetic component in Mycobacterium tuberculosis infection and disease progression. However, genomic studies of tuberculosis susceptibility have been disappointing compared with that of other complex disorders. Recently the field has explored alternative strategies to facilitate locus discovery. Results emanating from these efforts during the...

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Antitubercular Agents
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomics
Global Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium tuberculosis

Pharmacogenomic Variants

Tuberculosis, Pulmonary

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PMID: 32101905
DOI: 10.1097/MCP.0000000000000672

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