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Histone acetylome-wide association study of tuberculosis

2019-05-21

Abstract excerpt

Host-cell chromatin changes are thought to play an important role in the pathogenesis of infectious diseases. Here, we describe the first histone acetylome-wide association study (HAWAS) of an infectious disease, based on genome-wide H3K27 acetylation profiling of peripheral granulocytes and monocytes from subjects with active Mycobacterium tuberculosis ( Mtb ) infection and healthy controls. We detected >2,000...

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Identifiers and source

Literature Corpus work
0587505c-e4aa-559c-a26d-0ac02fe41b68
DOI
10.1101/644112
Open publication

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