Article

Central role for fast nociceptors in mechanical nocifensive behavior and sensitization

2025-11-13

Abstract excerpt

Nociceptors, primary afferent nerve fibers that signal noxious stimuli, are broadly divided into slowly conducting unmyelinated C fibers and fast-conducting myelinated A fibers. Whereas C-nociceptors have been extensively studied, considerably less is known about the function of A-nociceptors. To address this gap, we developed an intersectional genetic approach for robust and selective interrogation and manipulati...

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Literature Corpus work: 0c678c4d-96f3-5ad0-9019-beca0a577dd4
DOI: 10.1101/2025.11.12.688120

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