Article

Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors

2017-06-13

Abstract excerpt

The human distal limbs have a high spatial acuity for noxious stimuli but a low density of pain-sensing neurites. To elucidate mechanisms underlying the ‘pain fovea’, we sparsely traced non-peptidergic nociceptors across the body using a newly generated MrgprD CreERT2 mouse line. We found that mouse plantar paw skin also has a low density of MrgprD + neurites, and individual arbors in different locations are co...

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Literature Corpus work: a86fdae9-4c52-528d-92e6-bc56b75809cf
DOI: 10.1101/149641

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