scGRNom: a computational pipeline of integrative multi-omics analyses for predicting cell-type disease genes and regulatory networks.

Abstract excerpt

Understanding cell-type-specific gene regulatory mechanisms from genetic variants to diseases remains challenging. To address this, we developed a computational pipeline, scGRNom (single-cell Gene Regulatory Network prediction from multi-omics), to predict cell-type disease genes and regulatory networks including transcription factors and regulatory elements. With applications to schizophrenia and Alzheimer's...

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