Article

RNA-seq Analysis Reveals Upregulation in ER -Stress-Related Genes Upon LCL-161 Treatment in SH-SY5Y Human Neuroblastoma Cells

2022-08-08

Abstract excerpt

<h4>Background: </h4> SMAC mimetics (SM) are compounds that are developed on secondary mitochondria-derived activators of caspase (SMAC) protein structure and sensitize cancer cells to cell death, either alone or in the presence of death ligands or chemotherapies. However, their efficacy as a single agent or in combination with chemotherapy is highly variable and limited. In this study, we aimed to identify the tr...

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Literature Corpus work: 0c051b25-d653-518b-a303-9858a0073a7f
DOI: 10.21203/rs.3.rs-1921627/v1

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