Article

Alteration in long noncoding RNAs in response to oxidative stress and ladostigil in SH-SY5Y cells

2022-02-20

Abstract excerpt

Microglia activation causes neuroinflammation, which is a hallmark of neurodegenerative disorders, brain injury, and aging. Ladostigil, a bifunctional reagent with antioxidant and anti-inflammatory properties, reduced microglial activation and enhanced brain functioning in elderly rats. In this study, we studied SH-SY5Y, a human neuroblastoma cell line, and tested viability in the presence of hydrogen peroxide and...

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Literature Corpus work: 827b10fe-7992-5ce4-9253-2d7c74b8b1a2
DOI: 10.1101/2022.02.20.481187

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