Back to search

Article

Nlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebrates

2022-11-18

Abstract excerpt

<title>Abstract</title> <p>Hematopoietic stem and progenitor cells (HSPCs) generate all of the lineages of blood cells throughout the lifespan of vertebrates. The emergence of HSPCs occurs through the hemogenic endothelial (HE) to hematopoietic transition (EHT) process, which is finely-tuned by a variety of signaling pathways. Previous studies have emerged the essential roles of pattern-recognition receptors such...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0be1e801-e841-5985-a4af-9ad930dbfd63
DOI
10.21203/rs.3.rs-2266291/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Nlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebratesDOI 10.21203/rs.3.rs-2266291/v1
Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPasesSemantic proximity
Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPasesSemantic proximity
Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cellsSemantic proximity
MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryoSemantic proximity
MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryoSemantic proximity
The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1β maturation and gasdermin E–mediated pyroptosisSemantic proximity
NOD-like receptors: versatile cytosolic sentinels.Semantic proximity
<scp>NOD</scp>‐like receptors interfacing the immune and reproductive systemsSemantic proximity
Embryonic hematopoiesis.Semantic proximity
Toll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic diseases.Semantic proximity
Hematopoietic stem and progenitor cell heterogeneity is inherited from the embryonic hemogenic endotheliumSemantic proximity
NLR functions beyond pathogen recognition.Semantic proximity
Select a neighboring publication to make it the new centre.