Article
NOD-like receptors: versatile cytosolic sentinels.
Physiological reviews - 1 Jan 2015
Motta Vinicius, Soares Fraser, Sun Tian, Philpott Dana J
Abstract excerpt
Nucleotide binding oligomerization domain (NOD)-like receptors are cytoplasmic pattern-recognition receptors that together with RIG-I-like receptor (retinoic acid-inducible gene 1), Toll-like receptor (TLR), and C-type lectin families make up the innate pathogen pattern recognition system. There are 22 members of NLRs in humans, 34 in mice, and even a larger number in some invertebrates like sea urchins, which...
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