Article
NLR functions beyond pathogen recognition.
Nature immunology - 1 Feb 2011
Kufer Thomas A, Sansonetti Philippe J
Abstract excerpt
The last 10 years have witnessed the identification of a new class of intracellular pattern-recognition molecules--the nucleotide-binding domain and leucine-rich repeat-containing family (NLR). Members of this family garnered interest as pattern-recognition receptors able to trigger inflammatory responses against pathogens. Many studies support a pathogen-recognition function for human NLR proteins and shed light...
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