Article

Wilms tumour resulting from paternal transmission of a TRIM28 pathogenic variant – A first report

2023-11-22

Abstract excerpt

<title>Abstract</title> <p>Wilms tumour (nephroblastoma) is a renal embryonal tumour that is frequently caused by constitutional variants in a small range of cancer predisposition genes. <italic>TRIM28</italic> has recently been identified as one such gene. Previously, observational data strongly suggested a parent of origin effect, whereby Wilms tumour only occurred following maternal inheritance of a pathogenic...

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Literature Corpus work: 0b513933-6167-5409-ad91-af34e79a2bb8
DOI: 10.21203/rs.3.rs-3616311/v1

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