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Article

Comprehensive Analysis of Hepatitis B Virus Promoter Region Mutations

2018-10-15

Abstract excerpt

Over 250 million people are infected chronically with hepatitis B virus (HBV), the leading cause of liver cancer worldwide. HBV persists due in part to its compact, stable minichromosome, the covalently-closed, circular DNA (cccDNA), which resides in the hepatocytes’ nuclei. Current therapies target downstream replication products, however, a true virological cure will require targeting the cccDNA. Finding t...

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Literature Corpus work
0affe314-066d-59cf-86ea-fc6f1de5ae19
DOI
10.20944/preprints201810.0314.v1
Open publication

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Comprehensive Analysis of Hepatitis B Virus Promoter Region MutationsDOI 10.20944/preprints201810.0314.v1
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