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Variations and mutations in the hepatitis B virus genome and their associations with clinical characteristics

1 Jan 2015

Abstract excerpt

Hepatitis B virus (HBV) infection is major global issue, because chronic HBV infection is strongly associated with liver cancer. HBV spread worldwide with various mutations and variations. This variability, called quasispecies, is derived from no proof-reading capacity of viral reverse transcriptase. So far, thousands of studies reported that the variety of genome is closely related to the geographic distribution...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25848482
DOI: 10.4254/wjh.v7.i3.583

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