Article

Accelerated and Localized Synucleinopathy in a Hybrid Mouse Model: Implications for Positron Emission Tomography Studies

2025-10-30

Abstract excerpt

<title>Abstract</title> <p>BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by α-synuclein (α-syn) aggregation, dopamine (DA) neuron loss, and neuroinflammation. Synucleinopathy, the α-syn-related pathology, is the central to the pathogenetic processes observed in the brains of patients with PD, dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). We are seeking an...

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Literature Corpus work: 0ae236a4-d2f8-53b5-9c8a-e27db7b982a7
DOI: 10.21203/rs.3.rs-7821065/v1

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