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Article

A computational model of inhibition of HIV-1 by interferon-alpha

2015-11-09

Abstract excerpt

Type 1 interferons such as interferon-alpha (IFN α ) inhibit replication of Human immunodeficiency virus (HIV-1) by upregulating the expression of genes that interfere with specific steps in the viral life cycle. This pathway thus represents a potential target for immune-based therapies that can alter the dynamics of host-virus interactions to benefit the host. To obtain a deeper mechanistic understanding of how...

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Literature Corpus work
0ac61fe5-b86f-58bd-91e7-23c169a47389
DOI
10.1101/031005
Open publication

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A computational model of inhibition of HIV-1 by interferon-alphaDOI 10.1101/031005
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