Article
Systems mapping of HIV-1 infection.
BMC genetics - 23 Oct 2012
Hou Wei, Sui Yihan, Wang Zhong, Wang Yaqun, Wang Ningtao, Liu Jingyuan, Li Yao, Goodenow Maureen, Yin Li, Wang Zuoheng, Wu Rongling
Abstract excerpt
Mathematical models of viral dynamics in vivo provide incredible insights into the mechanisms for the nonlinear interaction between virus and host cell populations, the dynamics of viral drug resistance, and the way to eliminate virus infection from individual patients by drug treatment. The integration of these mathematical models with high-throughput genetic and genomic data within a statistical framework will...
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