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Article

Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo.

Proceedings of the National Academy of Sciences of the United States of America - 21 Feb 2012

Pillai Satish K, Abdel-Mohsen Mohamed, Guatelli John, Skasko Mark, Monto Alexander, Fujimoto Katsuya, Yukl Steven, Greene Warner C, Kovari Helen, Rauch Andri, Fellay Jacques, Battegay Manuel, Hirschel Bernard, Witteck Andrea, Bernasconi Enos, Ledergerber Bruno, Günthard Huldrych F, Wong Joseph K

Abstract excerpt

The antiviral potency of the cytokine IFN-α has been long appreciated but remains poorly understood. A number of studies have suggested that induction of the apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 (APOBEC3) and bone marrow stromal cell antigen 2 (BST-2/tetherin/CD317) retro...

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Identifiers

PMID: 22315404
DOI: 10.1073/pnas.1111573109
PMCID: PMC3286922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22315404-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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