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Article

Multi-scale modeling of HIV infection in vitro and APOBEC3G-based anti-retroviral therapy.

PLoS computational biology - 1 Feb 2012

Hosseini Iraj, Mac Gabhann Feilim

Abstract excerpt

The human APOBEC3G is an innate restriction factor that, in the absence of Vif, restricts HIV-1 replication by inducing excessive deamination of cytidine residues in nascent reverse transcripts and inhibiting reverse transcription and integration. To shed light on impact of A3G-Vif interactions o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to vif Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 22346743
DOI: 10.1371/journal.pcbi.1002371
PMCID: PMC3276540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22346743-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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