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Mathematical analysis of antiretroviral therapy aimed at HIV-1 eradication or maintenance of low viral loads.

Journal of theoretical biology - 7 May 1998

Wein L M, D'Amato R M, Perelson A S

Abstract excerpt

Motivated by the ability of combinations of antiretroviral agents to sustain viral suppression in HIV-1-infected individuals, we analyse the transient and steady-state behavior of a mathematical model of HIV-1 dynamics in vivo in order to predict whether these drug regimens can eradicate HIV-1 or...

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Mutation
Drug Resistance, Microbial
HIV-1
Genes, Viral
HIV Infections
CD4-Positive T-Lymphocytes

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Antiviral Agents

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PMID: 9628841
DOI: 10.1006/jtbi.1997.0622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9628841-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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