Article

AMES: Automated evaluation of sarcomere structures in cardiomyocytes

2021-08-08

Abstract excerpt

<h4>Background</h4> Arrhythmias are severe cardiac diseases and lethal if untreated. To serve as an in vitro drug testing option for anti-arrhythmic agents, cardiomyocytes are being generated in vitro from induced pluripotent stem cells (iPSCs). Unfortunately, these generated cardiomyocytes resemble fetal cardiac tissue rather than adult cardiomyocytes. An automated tool for an unbiased evaluation of cardiomyocyt...

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Literature Corpus work: 204747c8-7f6b-5fd0-b514-4efdb6f9ae6f
DOI: 10.1101/2021.08.06.455455

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