Article

Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle

2021-01-21

Abstract excerpt

<h4>ABSTRACT</h4> Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess muscle health. Here, we test and apply Cellpose, a recently developed deep learning algorithm, to automatically segment myofibers within murine skeletal muscle. We first show that...

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Literature Corpus work: 9fc80b7c-5042-5c7a-871b-8dbc6ee3b4b3
DOI: 10.1101/2021.01.20.427432

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