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Article

Structural phenotyping of stem cell-derived cardiomyocytes.

Stem cell reports - 10 Mar 2015

Pasqualini Francesco Silvio, Sheehy Sean Paul, Agarwal Ashutosh, Aratyn-Schaus Yvonne, Parker Kevin Kit

Abstract excerpt

Structural phenotyping based on classical image feature detection has been adopted to elucidate the molecular mechanisms behind genetically or pharmacologically induced changes in cell morphology. Here, we developed a set of 11 metrics to capture the increasing sarcomere organization that occurs intracellularly during striated muscle cell development. To test our metrics, we analyzed the localization of the...

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Identifiers

PMID: 25733020
DOI: 10.1016/j.stemcr.2015.01.020
PMCID: PMC4375945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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