Article
Improving brain age estimates with deep learning leads to identification of novel genetic factors associated with brain aging.
Neurobiology of aging - 1 Sept 2021
Ning Kaida, Duffy Ben A, Franklin Meredith, Matloff Will, Zhao Lu, Arzouni Nibal, Sun Fengzhu, Toga Arthur W
Abstract excerpt
To study genetic factors associated with brain aging, we first need to quantify brain aging. Statistical models have been created for estimating the apparent age of the brain, or predicted brain age (PBA), using imaging data. Recent studies have refined these models to obtain a more accurate PBA, but research has yet to demonstrate the scientific value of doing so. Here, we show that a more accurate PBA leads to...
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