Article

Human mitochondrial protein complexes revealed by large-scale coevolution analysis and deep learning-based structure modeling

2021-09-14

Abstract excerpt

Recent development of deep-learning methods has led to a breakthrough in the prediction accuracy of 3-dimensional protein structures. Extending these methods to protein pairs is expected to allow large-scale detection of protein-protein interactions and modeling protein complexes at the proteome level. We applied RoseTTAFold and AlphaFold2, two of the latest deep-learning methods for structure predictions, to anal...

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Literature Corpus work: 0a2e4b9a-bd83-56a1-9db4-f578e490b2df
DOI: 10.1101/2021.09.14.460228

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