Article

SNP-CRISPR: a web tool for SNP-specific genome editing

2019-11-19

Abstract excerpt

<h4>ABSTRACT</h4> CRISPR-Cas9 is a powerful genome editing technology in which a single guide RNA (sgRNA) confers target site specificity to achieve Cas9-mediated genome editing. Numerous sgRNA design tools have been developed based on reference genomes for humans and model organisms. However, existing resources are not optimal as genetic mutations or single nucleotide polymorphisms (SNPs) within the targeting re...

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Literature Corpus work: 0a11f4b2-52fd-5372-8187-cac3bfe91fb1
DOI: 10.1101/847277

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