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SNP-CRISPR: A Web Tool for SNP-Specific Genome Editing.

G3 (Bethesda, Md.) - 6 Feb 2020

Chen Chiao-Lin, Rodiger Jonathan, Chung Verena, Viswanatha Raghuvir, Mohr Stephanie E, Hu Yanhui, Perrimon Norbert

Abstract excerpt

CRISPR-Cas9 is a powerful genome editing technology in which a single guide RNA (sgRNA) confers target site specificity to achieve Cas9-mediated genome editing. Numerous sgRNA design tools have been developed based on reference genomes for humans and model organisms. However, existing resources are not optimal as genetic mutations or single nucleotide polymorphisms (SNPs) within the targeting region affect the...

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Identifiers

PMID: 31822517
DOI: 10.1534/g3.119.400904
PMCID: PMC7003079

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Source receipt: pubmed, retrieved 7 Sept 2026.

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