Article

Disentangling the Complex Relationships Between Autoimmune Diseases and Cancer Through Polygenic Risk Scores: Evidence from a Large Prospective Study

2025-05-07

Abstract excerpt

<title>Abstract</title> <p>Although prior studies have reported a link between autoimmunity and carcinogenesis, the roles of genetic factors and potential mediators involved in this process remain elusive. We constructed disease-specific and combined polygenic risk scores (PRSs) for 6 common autoimmune diseases (AIDs) (systemic lupus erythematosus [SLE], rheumatoid arthritis, multiple sclerosis, Crohn's disease,...

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Literature Corpus work: 09ed6f6e-13c5-5dd1-b260-4cedcd084b53
DOI: 10.21203/rs.3.rs-6491161/v1

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