Article
Crossroads between autoimmunity and cancer: underlying mechanisms and clinical implications.
Physiological reviews - 1 Apr 2026
Gjyrezi Ada, Skarlis Charalampos, Mavragani Clio, Giannakakou Paraskevi
Abstract excerpt
Autoimmune diseases arise from an aberrant immune response against self-antigens, whereas cancer often develops when the immune system fails to effectively detect and destroy malignant cells. Although historically viewed as distinct entities with opposing immune mechanisms, recent findings highlight significant overlaps in their immunological pathways. This review explores the intricate interplay between...
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