Divergent autoimmune genetic landscapes in diabetic and non-diabetic individuals.

doi:10.1186/s12863-026-01452-4

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Article

Divergent autoimmune genetic landscapes in diabetic and non-diabetic individuals.

BMC genomic data - 14 Jun 2026

Shravya R V, Ananthakrishnan A I, Das Ranajit

Abstract excerpt

BACKGROUND: Type 2 diabetes (T2D) and autoimmune diseases are complex disorders shaped by genetic, immunological, and environmental factors. However, differences in genetic susceptibility to autoimmune disorders between diabetic and non-diabetic individuals remain poorly understood, particularly within the Indian population. This study aimed to compare polygenic susceptibility to multiple autoimmune diseases...

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Topics

Humans
Diabetes Mellitus, Type 2
Genetic Predisposition to Disease
Genetic Risk Score
India
Autoimmune Diseases
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Arthritis, Rheumatoid

Middle Aged

Lupus Erythematosus, Systemic

Polymorphism, Single Nucleotide

Multifactorial Inheritance

Genome-Wide Association Study

Source

Open in PubMed Open full text

Identifiers

PMID: 42289657
DOI: 10.1186/s12863-026-01452-4
PMCID: PMC13555873

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