Article

Genetic editing of primary human dorsal root ganglion neurons using CRISPR-Cas9 with functional confirmation

2024-04-03

Abstract excerpt

CRISPR-Cas9 editing is now the leading method for genome editing and is being advanced for the treatment of human disease. CRIPSR editing could have many applications for treatment of neurological diseases, including pain but traditional viral vector delivery approaches have neurotoxicity limiting their use. Overcoming these issues could open the door for genome editing treatments for diseases like intractable pai...

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Literature Corpus work: 09b7d10b-470c-5737-8ec8-b7c78ee924c0
DOI: 10.1101/2024.04.02.587857

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